Project TitleProteomic profiling of neutrophilic, iron-oxidizing Mariprofundus ferrooxydans, strain PV-1
AcronymProteomic profiling of Mariprofundus ferrooxydans
URLhttps://www.bco-dmo.org/project/632643
CreatedJanuary 13, 2016
ModifiedJanuary 13, 2016

Project Description

Description from C-DEBI website:
The aim of this proposal is to gain a better understanding of what subsets of proteins are actually being expressed during neutrophilic, microbial iron (Fe)-oxidation. The recently isolated Mariprofundus ferrooxydans, strain PV-1, will be used as a marine model organism to investigate proteomic differences under different Fe substrates: aqueous Fe2+ and solid Fe0. Two-dimensional gel electrophoresis (2D-GE) and shotgun proteomic methods (LC-MS/MS) will be employed to obtain results from the cultures grown under different conditions. The research being proposed would constitute the foundation for the development of diagnostic tools for the accordance, distribution, and activity level of Fe-oxidation, a globally important biogeochemical process at and below the ocean floor.

This project was funded by a C-DEBI Graduate Student Fellowship.

Project Maintainers

NameAffiliationRoleContact
Roman A. BarcoBigelow Laboratory for Ocean SciencesPrincipal Investigator
Katrina J. EdwardsUniversity of Southern California (USC)Co-Principal Investigator
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